Look, you aren’t alone. Millions of people worldwide are affected by anxiety and mood disorders. It is extremely common (not that that makes it normal, but yes, common). Anxiety and mood disorders are influenced by lots of things including genetics, lifestyle, environment, and what you eat. In recent years, omega-3 fatty acids have made a name for themselves for their role in brain health and emotional regulation. Within the framework of naturopathic medicine for anxiety, omega-3s are often highlighted as a foundational nutritional therapy that can support mental well-being in a gentle, holistic way.
Understanding Omega-3 Fatty Acids and Brain Health
Omega-3 fatty acids are essential fats, meaning the body cannot produce them on its own and they have to be eaten. The most important omega-3s for mental health are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These fats make up the brain cell membranes and help neurotransmitters function properly (aka help your brain talk to the rest of the body), decrease inflammation, and improve neuronal communication (aka help the nervous system communicate).
The brain is nearly 60% fat, and DHA in particular is super important for maintaining the brain’s ability to learn and adjust to changes and experiences. When omega-3 intake is low, these processes may become less efficient, potentially contributing to mood instability, anxiety, and depressive symptoms.
Omega-3s and Anxiety Disorders
Research suggests that omega-3 fatty acids may help reduce symptoms of anxiety by improving the body’s stress response. Chronic anxiety is usually linked to inflammation and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis (meaning, cortisol, your stress hormone, is released at the wrong time). Omega-3s, especially EPA, have anti-inflammatory properties that may help calm this stress response.
Within naturopathic medicine for anxiety, practitioners often emphasize reducing overall inflammation and supporting nervous system balance. Omega-3 supplementation or dietary intake is frequently recommended with lifestyle changes like stress management, improving sleep, mindfulness practices, and (my favorite) breathwork. Rather than masking symptoms, this approach aims to address underlying contributors to anxiety.
Mood Disorders and Emotional Regulation
Depression and other mood disorders have also been linked to low omega-3 levels. Several studies have found that individuals with depression often have lower concentrations of EPA and DHA in their blood. Omega-3s influence serotonin and dopamine signaling, neurotransmitters that are central to mood regulation and motivation.
EPA appears particularly helpful for depressive symptoms, while DHA supports overall brain structure and function. From a naturopathic perspective, improving nutritional deficiencies is a key step in restoring emotional balance. This aligns with the naturopathic medicine approach for anxiety and mood disorders, which prioritizes improving nutrition and gut health status as a cornerstone of mental health.
Food Sources to Increase Omega-3 Fatty Acids
Fatty Fish to Increase Omega-3s
One of the most effective and sustainable ways to increase omega-3 intake is through whole foods. Fatty fish are the richest dietary sources of EPA and DHA. Examples include salmon, sardines, mackerel, anchovies, and herring. Aim to have fatty fish two to three times per week.
Plant-Based Omega-3s
For those who do not eat fish, plant-based sources provide alpha-linolenic acid (ALA), which the body can partially convert into EPA and DHA. Foods rich in ALA include ground flaxseeds, chia seeds, walnuts, hemp seeds, and flaxseed oil. While conversion rates are relatively low, regular consumption still contributes to overall omega-3 intake.
Other Omega-3 Foods
Eggs enriched with omega-3s and grass-fed meats can also provide small amounts of these beneficial fats. In naturopathic practice, food quality is emphasized, as sustainably sourced and minimally processed foods tend to offer greater nutritional value.
Omega-3 Supplements
Supplementing with Omega-3s can also be a great approach to improving Omega-3 levels. There are lots of supplements out there and as with all supplements (but especially with Omega-3s), you can do more harm than good if you get the wrong ones. These are some of my favorites that have been tested well and have been shown to improve inflammation.
Integrating Omega-3s into a Holistic Approach
While omega-3 fatty acids are not a standalone cure for anxiety or mood disorders, they can be a powerful component of a comprehensive treatment plan. Naturopathic medicine for anxiety views mental health through a whole-person lens, integrating nutrition, lifestyle, emotional support, and, when necessary, supplementation.
Incorporating omega-3-rich foods into daily meals supports not only mental health but also cardiovascular, immune, and metabolic health. Over time, this nutritional strategy may help improve mood stability, reduce anxiety symptoms, and enhance overall resilience.
Let’s Connect!
My favorite way to get in Omega-3s is eating sardines! Have you tried them? I’d love to know if you have or what your favorite Omega-3 source is. Respond and let me know. And as always, please share this information with anyone you think would benefit!!



